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Skyrizi* (Risankizumab-Rzaa) — Medicare Part D spending

Abbvie US LLC* · Rank #167 by total Part D spend · CMS data year 2023

Medicare Part D spent $289,245,101 on Skyrizi* (Risankizumab-Rzaa) in 2023, the #167 drug by total Part D spending out of 3,598 drugs. That worked out to about $18,680.38 per dosage unit, $19,611 per claim and $60,184 per beneficiary, across 14,749 claims for 4,806 beneficiaries. Average spending per dosage unit rose +0.7% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Skyrizi* (Risankizumab-Rzaa) spending at a glance (2023)

MetricSkyrizi* (Risankizumab-Rzaa)
Total Part D spending (2023)$289,245,101
Total spending (2022)$251,093,665
Year-over-year change in total spending+15.2%
Average spending per dosage unit (2023)$18,680.38
Change in spend per dosage unit (YoY)+0.7%
Avg annual change per dosage unit (2019-2023 CAGR)+3.7%
Average spending per claim (2023)$19,611
Average spending per beneficiary (2023)$60,184
Total claims (2023)14,749
Beneficiaries (2023)4,806
Total dosage units (2023)27,777
Manufacturer(s)Abbvie US LLC*
National rank by total spend (of 3,598 drugs)#167

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Skyrizi* (Risankizumab-Rzaa): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$251,093,665$289,245,101+15.2%
Avg spend per dosage unit$18,551.61$18,680.38+0.7%
Avg spend per claim$18,841$19,611
Avg spend per beneficiary$58,557$60,184
Total claims13,32714,749
Beneficiaries4,2884,806

How Skyrizi* compares with nearby drugs

Drugs with total Part D spending closest to Skyrizi* (Risankizumab-Rzaa):

Skyrizi* (Risankizumab-Rzaa) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Skyrizi* (Risankizumab-Rzaa) (this drug, #167)$289,245,101$18,680.38+0.7%
Radicava Ors (Edaravone) (#165)$293,678,844$271.04+2.1%
Ezetimibe (#166)$290,177,168$0.57-29.0%
Pregabalin (#168)$287,950,539$0.51-5.1%
Levemir (Insulin Detemir) (#169)$287,253,250$32.63+0.7%
Bydureon Bcise (Exenatide Microspheres) (#170)$284,056,759$244.15+3.1%

Frequently asked questions

How much does Medicare Part D spend on Skyrizi*?

Medicare Part D spent $289,245,101 on Skyrizi* (Risankizumab-Rzaa) in 2023 (the latest CMS data year), across 14,749 claims for 4,806 beneficiaries. That ranks #167 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Skyrizi*?

In 2023, the weighted average Medicare Part D spending per dosage unit for Skyrizi* (Risankizumab-Rzaa) was $18,680.38. Compared with 2022 it rose +0.7%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Skyrizi*?

CMS attributes Skyrizi* (Risankizumab-Rzaa) to Abbvie US LLC* in the 2023 Part D spending file. Average spending per claim was $19,611 and per beneficiary $60,184.

Is the Skyrizi* figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20