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Skyrizi Pen (Risankizumab-Rzaa) — Medicare Part D spending

Abbvie US LLC · Rank #41 by total Part D spend · CMS data year 2023

Medicare Part D spent $1,189,321,833 on Skyrizi Pen (Risankizumab-Rzaa) in 2023, the #41 drug by total Part D spending out of 3,598 drugs. That worked out to about $20,593.60 per dosage unit, $20,713 per claim and $65,326 per beneficiary, across 57,419 claims for 18,206 beneficiaries. Average spending per dosage unit rose +8.1% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Skyrizi Pen (Risankizumab-Rzaa) spending at a glance (2023)

MetricSkyrizi Pen (Risankizumab-Rzaa)
Total Part D spending (2023)$1,189,321,833
Total spending (2022)$594,742,286
Year-over-year change in total spending+100.0%
Average spending per dosage unit (2023)$20,593.60
Change in spend per dosage unit (YoY)+8.1%
Avg annual change per dosage unit (2019-2023 CAGR)+8.7%
Average spending per claim (2023)$20,713
Average spending per beneficiary (2023)$65,326
Total claims (2023)57,419
Beneficiaries (2023)18,206
Total dosage units (2023)57,752
Manufacturer(s)Abbvie US LLC
National rank by total spend (of 3,598 drugs)#41

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Skyrizi Pen (Risankizumab-Rzaa): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$594,742,286$1,189,321,833+100.0%
Avg spend per dosage unit$19,046.38$20,593.60+8.1%
Avg spend per claim$19,186$20,713
Avg spend per beneficiary$57,469$65,326
Total claims30,99857,419
Beneficiaries10,34918,206

How Skyrizi Pen compares with nearby drugs

Drugs with total Part D spending closest to Skyrizi Pen (Risankizumab-Rzaa):

Skyrizi Pen (Risankizumab-Rzaa) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Skyrizi Pen (Risankizumab-Rzaa) (this drug, #41)$1,189,321,833$20,593.60+8.1%
Shingrix (Varicella-Zoster Ge/As01b/PF) (#39)$1,211,171,028$212.26+8.4%
Humalog Kwikpen U-100 (Insulin Lispro) (#40)$1,208,385,334$35.80+0.4%
Austedo (Deutetrabenazine) (#42)$1,123,439,045$103.61+6.5%
Cabometyx (Cabozantinib S-Malate) (#43)$1,109,315,042$878.24+8.7%
Repatha Sureclick (Evolocumab) (#44)$1,092,210,722$286.44+8.3%

Frequently asked questions

How much does Medicare Part D spend on Skyrizi Pen?

Medicare Part D spent $1,189,321,833 on Skyrizi Pen (Risankizumab-Rzaa) in 2023 (the latest CMS data year), across 57,419 claims for 18,206 beneficiaries. That ranks #41 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Skyrizi Pen?

In 2023, the weighted average Medicare Part D spending per dosage unit for Skyrizi Pen (Risankizumab-Rzaa) was $20,593.60. Compared with 2022 it rose +8.1%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Skyrizi Pen?

CMS attributes Skyrizi Pen (Risankizumab-Rzaa) to Abbvie US LLC in the 2023 Part D spending file. Average spending per claim was $20,713 and per beneficiary $65,326.

Is the Skyrizi Pen figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20