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Skyrizi On-Body (Risankizumab-Rzaa) — Medicare Part D spending

Abbvie US LLC · Rank #337 by total Part D spend · CMS data year 2023

Medicare Part D spent $125,306,777 on Skyrizi On-Body (Risankizumab-Rzaa) in 2023, the #337 drug by total Part D spending out of 3,598 drugs. That worked out to about $9,002.43 per dosage unit, $20,589 per claim and $69,499 per beneficiary, across 6,086 claims for 1,803 beneficiaries. Average spending per dosage unit rose +13.5% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Skyrizi On-Body (Risankizumab-Rzaa) spending at a glance (2023)

MetricSkyrizi On-Body (Risankizumab-Rzaa)
Total Part D spending (2023)$125,306,777
Total spending (2022)$4,310,899
Year-over-year change in total spending+2806.7%
Average spending per dosage unit (2023)$9,002.43
Change in spend per dosage unit (YoY)+13.5%
Avg annual change per dosage unit (2019-2023 CAGR)+13.5%
Average spending per claim (2023)$20,589
Average spending per beneficiary (2023)$69,499
Total claims (2023)6,086
Beneficiaries (2023)1,803
Total dosage units (2023)14,249
Manufacturer(s)Abbvie US LLC
National rank by total spend (of 3,598 drugs)#337

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Skyrizi On-Body (Risankizumab-Rzaa): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$4,310,899$125,306,777+2806.7%
Avg spend per dosage unit$7,933.20$9,002.43+13.5%
Avg spend per claim$18,991$20,589
Avg spend per beneficiary$23,949$69,499
Total claims2276,086
Beneficiaries1801,803

How Skyrizi On-Body compares with nearby drugs

Drugs with total Part D spending closest to Skyrizi On-Body (Risankizumab-Rzaa):

Skyrizi On-Body (Risankizumab-Rzaa) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Skyrizi On-Body (Risankizumab-Rzaa) (this drug, #337)$125,306,777$9,002.43+13.5%
Nano 2nd Gen Pen Needle (Pen Needle, Diabetic) (#335)$127,016,041$0.54+3.1%
Gilenya (Fingolimod HCl) (#336)$125,490,483$356.52+6.4%
Carbidopa-Levodopa (Carbidopa/Levodopa) (#338)$125,111,276$0.20-5.1%
Humulin 70/30 Kwikpen (Insulin NPh Hum/Reg Insulin Hm) (#339)$124,346,168$25.46+0.4%
Iclusig (Ponatinib HCl) (#340)$123,338,680$686.96+6.1%

Frequently asked questions

How much does Medicare Part D spend on Skyrizi On-Body?

Medicare Part D spent $125,306,777 on Skyrizi On-Body (Risankizumab-Rzaa) in 2023 (the latest CMS data year), across 6,086 claims for 1,803 beneficiaries. That ranks #337 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Skyrizi On-Body?

In 2023, the weighted average Medicare Part D spending per dosage unit for Skyrizi On-Body (Risankizumab-Rzaa) was $9,002.43. Compared with 2022 it rose +13.5%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Skyrizi On-Body?

CMS attributes Skyrizi On-Body (Risankizumab-Rzaa) to Abbvie US LLC in the 2023 Part D spending file. Average spending per claim was $20,589 and per beneficiary $69,499.

Is the Skyrizi On-Body figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20