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Shingrix (Varicella-Zoster Ge/As01b/PF) — Medicare Part D spending

Glaxosmithkline · Rank #39 by total Part D spend · CMS data year 2023

Medicare Part D spent $1,211,171,028 on Shingrix (Varicella-Zoster Ge/As01b/PF) in 2023, the #39 drug by total Part D spending out of 3,598 drugs. That worked out to about $212.26 per dosage unit, $213 per claim and $311 per beneficiary, across 5,696,455 claims for 3,894,337 beneficiaries. Average spending per dosage unit rose +8.4% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Shingrix (Varicella-Zoster Ge/As01b/PF) spending at a glance (2023)

MetricShingrix (Varicella-Zoster Ge/As01b/PF)
Total Part D spending (2023)$1,211,171,028
Total spending (2022)$767,548,020
Year-over-year change in total spending+57.8%
Average spending per dosage unit (2023)$212.26
Change in spend per dosage unit (YoY)+8.4%
Avg annual change per dosage unit (2019-2023 CAGR)+6.3%
Average spending per claim (2023)$213
Average spending per beneficiary (2023)$311
Total claims (2023)5,696,455
Beneficiaries (2023)3,894,337
Total dosage units (2023)5,706,085
Manufacturer(s)Glaxosmithkline
National rank by total spend (of 3,598 drugs)#39

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Shingrix (Varicella-Zoster Ge/As01b/PF): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$767,548,020$1,211,171,028+57.8%
Avg spend per dosage unit$195.80$212.26+8.4%
Avg spend per claim$196$213
Avg spend per beneficiary$274$311
Total claims3,919,8315,696,455
Beneficiaries2,803,3743,894,337

How Shingrix compares with nearby drugs

Drugs with total Part D spending closest to Shingrix (Varicella-Zoster Ge/As01b/PF):

Shingrix (Varicella-Zoster Ge/As01b/PF) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Shingrix (Varicella-Zoster Ge/As01b/PF) (this drug, #39)$1,211,171,028$212.26+8.4%
Calquence (Acalabrutinib Maleate) (#37)$1,286,819,830$255.96+2.2%
Tagrisso (Osimertinib Mesylate) (#38)$1,231,962,204$569.45+4.0%
Humalog Kwikpen U-100 (Insulin Lispro) (#40)$1,208,385,334$35.80+0.4%
Skyrizi Pen (Risankizumab-Rzaa) (#41)$1,189,321,833$20,593.60+8.1%
Austedo (Deutetrabenazine) (#42)$1,123,439,045$103.61+6.5%

Frequently asked questions

How much does Medicare Part D spend on Shingrix?

Medicare Part D spent $1,211,171,028 on Shingrix (Varicella-Zoster Ge/As01b/PF) in 2023 (the latest CMS data year), across 5,696,455 claims for 3,894,337 beneficiaries. That ranks #39 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Shingrix?

In 2023, the weighted average Medicare Part D spending per dosage unit for Shingrix (Varicella-Zoster Ge/As01b/PF) was $212.26. Compared with 2022 it rose +8.4%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Shingrix?

CMS attributes Shingrix (Varicella-Zoster Ge/As01b/PF) to Glaxosmithkline in the 2023 Part D spending file. Average spending per claim was $213 and per beneficiary $311.

Is the Shingrix figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20