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Xeljanz XR (Tofacitinib Citrate) — Medicare Part D spending

Pfizer US Pharm · Rank #94 by total Part D spend · CMS data year 2023

Medicare Part D spent $585,772,572 on Xeljanz XR (Tofacitinib Citrate) in 2023, the #94 drug by total Part D spending out of 3,598 drugs. That worked out to about $191.75 per dosage unit, $6,227 per claim and $46,873 per beneficiary, across 94,068 claims for 12,497 beneficiaries. Average spending per dosage unit rose +6.8% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Xeljanz XR (Tofacitinib Citrate) spending at a glance (2023)

MetricXeljanz XR (Tofacitinib Citrate)
Total Part D spending (2023)$585,772,572
Total spending (2022)$591,107,821
Year-over-year change in total spending-0.9%
Average spending per dosage unit (2023)$191.75
Change in spend per dosage unit (YoY)+6.8%
Avg annual change per dosage unit (2019-2023 CAGR)+6.1%
Average spending per claim (2023)$6,227
Average spending per beneficiary (2023)$46,873
Total claims (2023)94,068
Beneficiaries (2023)12,497
Total dosage units (2023)3,054,923
Manufacturer(s)Pfizer US Pharm
National rank by total spend (of 3,598 drugs)#94

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Xeljanz XR (Tofacitinib Citrate): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$591,107,821$585,772,572-0.9%
Avg spend per dosage unit$179.57$191.75+6.8%
Avg spend per claim$5,817$6,227
Avg spend per beneficiary$42,304$46,873
Total claims101,61494,068
Beneficiaries13,97312,497

How Xeljanz XR compares with nearby drugs

Drugs with total Part D spending closest to Xeljanz XR (Tofacitinib Citrate):

Xeljanz XR (Tofacitinib Citrate) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Xeljanz XR (Tofacitinib Citrate) (this drug, #94)$585,772,572$191.75+6.8%
Descovy (Emtricitabine/Tenofov Alafenam) (#92)$589,840,789$75.49+6.7%
Metoprolol Succinate (#93)$587,676,864$0.26-0.9%
Albuterol Sulfate HFA (Albuterol Sulfate) (#95)$583,910,454$2.80-25.0%
Nubeqa (Darolutamide) (#96)$576,350,299$113.38+5.7%
Promacta (Eltrombopag Olamine) (#97)$557,676,106$397.68+11.3%

Frequently asked questions

How much does Medicare Part D spend on Xeljanz XR?

Medicare Part D spent $585,772,572 on Xeljanz XR (Tofacitinib Citrate) in 2023 (the latest CMS data year), across 94,068 claims for 12,497 beneficiaries. That ranks #94 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Xeljanz XR?

In 2023, the weighted average Medicare Part D spending per dosage unit for Xeljanz XR (Tofacitinib Citrate) was $191.75. Compared with 2022 it rose +6.8%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Xeljanz XR?

CMS attributes Xeljanz XR (Tofacitinib Citrate) to Pfizer US Pharm in the 2023 Part D spending file. Average spending per claim was $6,227 and per beneficiary $46,873.

Is the Xeljanz XR figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20