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Synjardy (Empagliflozin/Metformin HCl) — Medicare Part D spending

Boehringer Ing. · Rank #273 by total Part D spend · CMS data year 2023

Medicare Part D spent $163,646,663 on Synjardy (Empagliflozin/Metformin HCl) in 2023, the #273 drug by total Part D spending out of 3,598 drugs. That worked out to about $10.25 per dosage unit, $1,039 per claim and $4,575 per beneficiary, across 157,520 claims for 35,768 beneficiaries. Average spending per dosage unit rose +4.1% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Synjardy (Empagliflozin/Metformin HCl) spending at a glance (2023)

MetricSynjardy (Empagliflozin/Metformin HCl)
Total Part D spending (2023)$163,646,663
Total spending (2022)$126,415,038
Year-over-year change in total spending+29.5%
Average spending per dosage unit (2023)$10.25
Change in spend per dosage unit (YoY)+4.1%
Avg annual change per dosage unit (2019-2023 CAGR)+5.5%
Average spending per claim (2023)$1,039
Average spending per beneficiary (2023)$4,575
Total claims (2023)157,520
Beneficiaries (2023)35,768
Total dosage units (2023)15,968,209
Manufacturer(s)Boehringer Ing.
National rank by total spend (of 3,598 drugs)#273

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Synjardy (Empagliflozin/Metformin HCl): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$126,415,038$163,646,663+29.5%
Avg spend per dosage unit$9.84$10.25+4.1%
Avg spend per claim$971$1,039
Avg spend per beneficiary$4,310$4,575
Total claims130,200157,520
Beneficiaries29,33035,768

How Synjardy compares with nearby drugs

Drugs with total Part D spending closest to Synjardy (Empagliflozin/Metformin HCl):

Synjardy (Empagliflozin/Metformin HCl) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Synjardy (Empagliflozin/Metformin HCl) (this drug, #273)$163,646,663$10.25+4.1%
Prednisolone Acetate (#271)$163,897,057$6.24-6.3%
Ocaliva (Obeticholic Acid) (#272)$163,801,289$303.92+9.1%
Procrit (Epoetin Alfa) (#274)$163,098,995$538.47+2.5%
Arikayce (Amikacin Liposomal/Neb.Accessr) (#275)$161,637,429$63.38+7.9%
Zejula (Niraparib Tosylate) (#276)$161,500,239$396.21+43.1%

Frequently asked questions

How much does Medicare Part D spend on Synjardy?

Medicare Part D spent $163,646,663 on Synjardy (Empagliflozin/Metformin HCl) in 2023 (the latest CMS data year), across 157,520 claims for 35,768 beneficiaries. That ranks #273 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Synjardy?

In 2023, the weighted average Medicare Part D spending per dosage unit for Synjardy (Empagliflozin/Metformin HCl) was $10.25. Compared with 2022 it rose +4.1%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Synjardy?

CMS attributes Synjardy (Empagliflozin/Metformin HCl) to Boehringer Ing. in the 2023 Part D spending file. Average spending per claim was $1,039 and per beneficiary $4,575.

Is the Synjardy figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20