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Soliqua 100-33 (Insulin Glargine/Lixisenatide) — Medicare Part D spending

Sanofi-Aventis · Rank #163 by total Part D spend · CMS data year 2023

Medicare Part D spent $302,998,642 on Soliqua 100-33 (Insulin Glargine/Lixisenatide) in 2023, the #163 drug by total Part D spending out of 3,598 drugs. That worked out to about $59.80 per dosage unit, $1,148 per claim and $5,086 per beneficiary, across 263,822 claims for 59,571 beneficiaries. Average spending per dosage unit rose +5.8% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Soliqua 100-33 (Insulin Glargine/Lixisenatide) spending at a glance (2023)

MetricSoliqua 100-33 (Insulin Glargine/Lixisenatide)
Total Part D spending (2023)$302,998,642
Total spending (2022)$215,943,202
Year-over-year change in total spending+40.3%
Average spending per dosage unit (2023)$59.80
Change in spend per dosage unit (YoY)+5.8%
Avg annual change per dosage unit (2019-2023 CAGR)+5.7%
Average spending per claim (2023)$1,148
Average spending per beneficiary (2023)$5,086
Total claims (2023)263,822
Beneficiaries (2023)59,571
Total dosage units (2023)5,067,178
Manufacturer(s)Sanofi-Aventis
National rank by total spend (of 3,598 drugs)#163

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Soliqua 100-33 (Insulin Glargine/Lixisenatide): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$215,943,202$302,998,642+40.3%
Avg spend per dosage unit$56.51$59.80+5.8%
Avg spend per claim$1,090$1,148
Avg spend per beneficiary$4,831$5,086
Total claims198,066263,822
Beneficiaries44,69659,571

How Soliqua 100-33 compares with nearby drugs

Drugs with total Part D spending closest to Soliqua 100-33 (Insulin Glargine/Lixisenatide):

Soliqua 100-33 (Insulin Glargine/Lixisenatide) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Soliqua 100-33 (Insulin Glargine/Lixisenatide) (this drug, #163)$302,998,642$59.80+5.8%
Ubrelvy (Ubrogepant) (#161)$314,663,943$104.16+3.8%
Ninlaro (Ixazomib Citrate) (#162)$311,982,549$4,346.07+7.8%
Octagam (Immun Globg(IgG)/Malt/IgA Ov50) (#164)$300,823,932$18.28+5.0%
Radicava Ors (Edaravone) (#165)$293,678,844$271.04+2.1%
Ezetimibe (#166)$290,177,168$0.57-29.0%

Frequently asked questions

How much does Medicare Part D spend on Soliqua 100-33?

Medicare Part D spent $302,998,642 on Soliqua 100-33 (Insulin Glargine/Lixisenatide) in 2023 (the latest CMS data year), across 263,822 claims for 59,571 beneficiaries. That ranks #163 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Soliqua 100-33?

In 2023, the weighted average Medicare Part D spending per dosage unit for Soliqua 100-33 (Insulin Glargine/Lixisenatide) was $59.80. Compared with 2022 it rose +5.8%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Soliqua 100-33?

CMS attributes Soliqua 100-33 (Insulin Glargine/Lixisenatide) to Sanofi-Aventis in the 2023 Part D spending file. Average spending per claim was $1,148 and per beneficiary $5,086.

Is the Soliqua 100-33 figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20