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Mesalamine* (Mesalamine) — Medicare Part D spending

Multiple manufacturers (20) · Rank #179 by total Part D spend · CMS data year 2023

Medicare Part D spent $271,604,425 on Mesalamine* (Mesalamine) in 2023, the #179 drug by total Part D spending out of 3,598 drugs. That worked out to about $4.90 per dosage unit, $705 per claim and $2,853 per beneficiary, across 385,045 claims for 95,185 beneficiaries. Average spending per dosage unit fell -8.5% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Mesalamine* (Mesalamine) spending at a glance (2023)

MetricMesalamine* (Mesalamine)
Total Part D spending (2023)$271,604,425
Total spending (2022)$271,488,581
Year-over-year change in total spending+0.0%
Average spending per dosage unit (2023)$4.90
Change in spend per dosage unit (YoY)-8.5%
Avg annual change per dosage unit (2019-2023 CAGR)-7.7%
Average spending per claim (2023)$705
Average spending per beneficiary (2023)$2,853
Total claims (2023)385,045
Beneficiaries (2023)95,185
Total dosage units (2023)88,673,543
Manufacturer(s)Multiple manufacturers (20)
National rank by total spend (of 3,598 drugs)#179

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Mesalamine* (Mesalamine): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$271,488,581$271,604,425+0.0%
Avg spend per dosage unit$5.36$4.90-8.5%
Avg spend per claim$721$705
Avg spend per beneficiary$2,973$2,853
Total claims376,771385,045
Beneficiaries91,31595,185

How Mesalamine* compares with nearby drugs

Drugs with total Part D spending closest to Mesalamine* (Mesalamine):

Mesalamine* (Mesalamine) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Mesalamine* (Mesalamine) (this drug, #179)$271,604,425$4.90-8.5%
Aristada (Aripiprazole Lauroxil) (#177)$272,878,291$980.72+3.7%
Prezcobix (Darunavir/Cobicistat) (#178)$271,838,024$83.83+7.4%
Kerendia (Finerenone) (#180)$269,681,549$22.00+7.1%
Enbrel Mini (Etanercept) (#181)$269,006,301$1,837.74+9.9%
Rytary (Carbidopa/Levodopa) (#182)$266,869,488$4.49+8.7%

Frequently asked questions

How much does Medicare Part D spend on Mesalamine*?

Medicare Part D spent $271,604,425 on Mesalamine* (Mesalamine) in 2023 (the latest CMS data year), across 385,045 claims for 95,185 beneficiaries. That ranks #179 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Mesalamine*?

In 2023, the weighted average Medicare Part D spending per dosage unit for Mesalamine* (Mesalamine) was $4.90. Compared with 2022 it fell -8.5%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Mesalamine*?

CMS attributes Mesalamine* (Mesalamine) to Multiple manufacturers (20) in the 2023 Part D spending file. Average spending per claim was $705 and per beneficiary $2,853.

Is the Mesalamine* figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20