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Erleada (Apalutamide) — Medicare Part D spending

Janssen Biotech · Rank #47 by total Part D spend · CMS data year 2023

Medicare Part D spent $1,057,789,083 on Erleada (Apalutamide) in 2023, the #47 drug by total Part D spending out of 3,598 drugs. That worked out to about $156.58 per dosage unit, $14,835 per claim and $95,494 per beneficiary, across 71,302 claims for 11,077 beneficiaries. Average spending per dosage unit rose +32.1% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Erleada (Apalutamide) spending at a glance (2023)

MetricErleada (Apalutamide)
Total Part D spending (2023)$1,057,789,083
Total spending (2022)$877,671,428
Year-over-year change in total spending+20.5%
Average spending per dosage unit (2023)$156.58
Change in spend per dosage unit (YoY)+32.1%
Avg annual change per dosage unit (2019-2023 CAGR)+11.8%
Average spending per claim (2023)$14,835
Average spending per beneficiary (2023)$95,494
Total claims (2023)71,302
Beneficiaries (2023)11,077
Total dosage units (2023)7,909,683
Manufacturer(s)Janssen Biotech
National rank by total spend (of 3,598 drugs)#47

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Erleada (Apalutamide): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$877,671,428$1,057,789,083+20.5%
Avg spend per dosage unit$118.51$156.58+32.1%
Avg spend per claim$14,111$14,835
Avg spend per beneficiary$94,720$95,494
Total claims62,19771,302
Beneficiaries9,26611,077

How Erleada compares with nearby drugs

Drugs with total Part D spending closest to Erleada (Apalutamide):

Erleada (Apalutamide) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Erleada (Apalutamide) (this drug, #47)$1,057,789,083$156.58+32.1%
Xifaxan (Rifaximin) (#45)$1,090,110,101$54.93+7.3%
Dupixent Pen (Dupilumab) (#46)$1,081,417,351$951.72+7.5%
Tresiba Flextouch U-200 (Insulin Degludec) (#48)$1,047,670,731$71.71+0.9%
Levemir Flexpen (Insulin Detemir) (#49)$1,025,556,477$32.59
Opsumit (Macitentan) (#50)$1,018,837,123$424.66+8.3%

Frequently asked questions

How much does Medicare Part D spend on Erleada?

Medicare Part D spent $1,057,789,083 on Erleada (Apalutamide) in 2023 (the latest CMS data year), across 71,302 claims for 11,077 beneficiaries. That ranks #47 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Erleada?

In 2023, the weighted average Medicare Part D spending per dosage unit for Erleada (Apalutamide) was $156.58. Compared with 2022 it rose +32.1%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Erleada?

CMS attributes Erleada (Apalutamide) to Janssen Biotech in the 2023 Part D spending file. Average spending per claim was $14,835 and per beneficiary $95,494.

Is the Erleada figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20