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Cabenuva (Cabotegravir/Rilpivirine) — Medicare Part D spending

Viiv Healthcare · Rank #270 by total Part D spend · CMS data year 2023

Medicare Part D spent $165,605,768 on Cabenuva (Cabotegravir/Rilpivirine) in 2023, the #270 drug by total Part D spending out of 3,598 drugs. That worked out to about $1,140.51 per dosage unit, $6,547 per claim and $32,632 per beneficiary, across 25,295 claims for 5,075 beneficiaries. Average spending per dosage unit rose +4.4% from 2022. These are aggregate Medicare program figures (gross drug cost), not the price you pay.

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

Cabenuva (Cabotegravir/Rilpivirine) spending at a glance (2023)

MetricCabenuva (Cabotegravir/Rilpivirine)
Total Part D spending (2023)$165,605,768
Total spending (2022)$87,321,193
Year-over-year change in total spending+89.7%
Average spending per dosage unit (2023)$1,140.51
Change in spend per dosage unit (YoY)+4.4%
Avg annual change per dosage unit (2019-2023 CAGR)+4.7%
Average spending per claim (2023)$6,547
Average spending per beneficiary (2023)$32,632
Total claims (2023)25,295
Beneficiaries (2023)5,075
Total dosage units (2023)145,285
Manufacturer(s)Viiv Healthcare
National rank by total spend (of 3,598 drugs)#270

Source: CMS Medicare Part D Spending by Drug (data year 2023). Data as of June 2026.

2022 vs 2023

Cabenuva (Cabotegravir/Rilpivirine): year-over-year Medicare Part D figures. Per-claim/per-beneficiary "change" omitted because it mixes price and utilization. Source: CMS Medicare Part D Spending by Drug (data year 2023).
Metric20222023Change
Total spending$87,321,193$165,605,768+89.7%
Avg spend per dosage unit$1,092.82$1,140.51+4.4%
Avg spend per claim$5,924$6,547
Avg spend per beneficiary$27,110$32,632
Total claims14,74025,295
Beneficiaries3,2215,075

How Cabenuva compares with nearby drugs

Drugs with total Part D spending closest to Cabenuva (Cabotegravir/Rilpivirine):

Cabenuva (Cabotegravir/Rilpivirine) and its nearest-spend peers. Source: CMS Medicare Part D Spending by Drug (data year 2023), data year 2023.
Drug (rank)Total spend 2023Per dosage unitPer-unit YoY
Cabenuva (Cabotegravir/Rilpivirine) (this drug, #270)$165,605,768$1,140.51+4.4%
Levetiracetam* (Levetiracetam) (#268)$171,482,383$0.33-4.5%
Xywav (Sodium,Calcium,Mag,Pot Oxybate) (#269)$168,733,996$34.48+6.0%
Prednisolone Acetate (#271)$163,897,057$6.24-6.3%
Ocaliva (Obeticholic Acid) (#272)$163,801,289$303.92+9.1%
Synjardy (Empagliflozin/Metformin HCl) (#273)$163,646,663$10.25+4.1%

Frequently asked questions

How much does Medicare Part D spend on Cabenuva?

Medicare Part D spent $165,605,768 on Cabenuva (Cabotegravir/Rilpivirine) in 2023 (the latest CMS data year), across 25,295 claims for 5,075 beneficiaries. That ranks #270 of 3,598 drugs by total Part D spending. This is gross drug cost (Medicare, plan and beneficiary payments combined), not the price you personally pay.

What is the average spending per dosage unit for Cabenuva?

In 2023, the weighted average Medicare Part D spending per dosage unit for Cabenuva (Cabotegravir/Rilpivirine) was $1,140.51. Compared with 2022 it rose +4.4%. A "dosage unit" is one pill, tablet, milliliter or other billing unit, so this is not the price of a prescription.

Who makes Cabenuva?

CMS attributes Cabenuva (Cabotegravir/Rilpivirine) to Viiv Healthcare in the 2023 Part D spending file. Average spending per claim was $6,547 and per beneficiary $32,632.

Is the Cabenuva figure the price I pay?

No. These are aggregate Medicare Part D program figures (total gross drug cost and averages across all claims), published by CMS for transparency. Your out-of-pocket cost depends on your plan, formulary, deductible and coverage phase. Always check your plan and talk to your pharmacist or doctor.

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Source & what this means

Figures are from the CMS Medicare Part D Spending by Drug dataset (data year 2023, US public domain). "Total spending" is the gross drug cost — Medicare, plan and beneficiary payments combined — for Part D claims; it is not a list price, a negotiated price, or what any individual pays. Spending per dosage unit is volume-weighted across formulations. This is general public-spending information, not medical or pricing advice. Your own cost depends on your plan, deductible and coverage phase — verify with your Part D plan and a pharmacist. Data as of June 2026. See our methodology and disclaimer.

Last updated: 2026-06-20